TB-Profiler result

Run: SRR5485612
Summary

Run ID: SRR5485612

Sample name:

Date: 18-08-2022 08:22:06

Number of reads: 92824

Percentage reads mapped: 99.41

Strain:

Drug-resistance: MDR-TB

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
embB 4247431 p.Met306Ile missense_variant 1.0 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6501 p.Arg421Pro missense_variant 0.2
gyrA 6568 c.-734C>T upstream_gene_variant 0.17
rrs 1472302 n.457G>C non_coding_transcript_exon_variant 0.18
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.29
pncA 2289115 p.His43Asp missense_variant 0.2
pncA 2289319 c.-78C>G upstream_gene_variant 0.25