TB-Profiler result

Run: SRR5818418

Summary

Run ID: SRR5818418

Sample name:

Date: 04-04-2023 11:24:59

Number of reads: 75198

Percentage reads mapped: 65.58

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7268 c.-34C>T upstream_gene_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
rpoB 760294 p.Asn163Ile missense_variant 0.44
mmpR5 779303 p.Arg105His missense_variant 0.4
mmpL5 779361 c.-881C>T upstream_gene_variant 0.18
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.13
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv2752c 3065326 p.Ile289Thr missense_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 1.0
ethA 4326148 c.1326G>T synonymous_variant 1.0
ethA 4326439 p.Asn345Lys missense_variant 1.0
ethA 4326764 p.Ala237Val missense_variant 0.59
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407742 p.Arg154Pro missense_variant 1.0
gid 4407873 c.330G>T synonymous_variant 1.0