TB-Profiler result

Run: SRR5818447

Summary

Run ID: SRR5818447

Sample name:

Date: 04-04-2023 11:30:15

Number of reads: 705395

Percentage reads mapped: 99.86

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6458 p.Val407Leu missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
rpoB 760209 p.Asn135Asp missense_variant 0.2
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.16
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.22
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.15
fabG1 1673770 p.Ala111Pro missense_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
ahpC 2726184 c.-9A>C upstream_gene_variant 0.27
gid 4407588 c.615A>G synonymous_variant 1.0