TB-Profiler result

Run: SRR5985672
Summary

Run ID: SRR5985672

Sample name:

Date: 04-04-2023 11:46:04

Number of reads: 2206928

Percentage reads mapped: 96.75

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 9222 p.Asp641Tyr missense_variant 0.13
mmpL5 776497 c.1984C>T synonymous_variant 0.1
mmpL5 776871 p.Glu537Gly missense_variant 0.12
mmpR5 779369 p.Asp127Gly missense_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673380 c.-60C>G upstream_gene_variant 0.11
ndh 2102278 c.764delA frameshift_variant 0.11
katG 2155393 p.Asp240Gly missense_variant 0.11
PPE35 2168210 c.2403C>A synonymous_variant 0.13
Rv1979c 2222700 c.465C>G synonymous_variant 0.11
Rv1979c 2222752 p.Thr138Met missense_variant 0.12
pncA 2289551 c.-310C>A upstream_gene_variant 0.11
folC 2747542 c.57C>A synonymous_variant 0.12
Rv2752c 3065061 p.Tyr377* stop_gained 0.12
Rv2752c 3065952 c.240C>A synonymous_variant 0.14
thyX 3067361 p.Phe195Leu missense_variant 0.13
embB 4248705 p.Pro731Gln missense_variant 0.12
aftB 4267933 p.Ala302Pro missense_variant 0.25