TB-Profiler result

Run: SRR6045003
Summary

Run ID: SRR6045003

Sample name:

Date: 04-04-2023 11:51:05

Number of reads: 194265

Percentage reads mapped: 70.6

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491591 p.Lys270Met missense_variant 1.0
mshA 575495 p.Leu50Met missense_variant 0.25
mshA 575679 p.Asn111Ser missense_variant 1.0
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoB 760197 p.Ala131Thr missense_variant 0.25
rpoB 760822 p.Leu339Pro missense_variant 0.25
rpoB 762086 c.2280G>A synonymous_variant 0.33
rpoB 763151 p.Phe1115Leu missense_variant 0.25
rpoC 763768 c.400delT frameshift_variant 0.29
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777156 p.Arg442Gln missense_variant 0.5
mmpL5 778425 p.Ala19Val missense_variant 0.67
mmpS5 779569 c.-664G>T upstream_gene_variant 0.22
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303016 p.Val29Gly missense_variant 0.29
embR 1417206 p.Arg48Gly missense_variant 0.18
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
PPE35 2170454 c.159C>G synonymous_variant 0.25
PPE35 2170457 c.156G>C synonymous_variant 0.25
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2290090 c.-849C>T upstream_gene_variant 1.0
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
Rv2752c 3065008 p.Pro395Gln missense_variant 0.29
Rv2752c 3065057 p.Gly379Cys missense_variant 0.29
thyA 3074509 c.-38G>A upstream_gene_variant 0.33
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3449457 c.954C>T synonymous_variant 0.33
fprA 3473998 c.-9G>A upstream_gene_variant 1.0
fprA 3473998 c.-10_-9insA upstream_gene_variant 1.0
fprA 3475360 p.Arg452Trp missense_variant 0.33
fbiA 3640398 c.-145G>T upstream_gene_variant 0.13
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4246334 c.-180G>A upstream_gene_variant 0.22
ethA 4327411 p.Trp21Cys missense_variant 0.22
whiB6 4338595 c.-75delG upstream_gene_variant 1.0