TB-Profiler result

Run: SRR6046151
Summary

Run ID: SRR6046151

Sample name:

Date: 04-04-2023 12:12:01

Number of reads: 5678

Percentage reads mapped: 7.33

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoB 760274 c.468G>A synonymous_variant 1.0
rpoB 760283 c.477G>C synonymous_variant 1.0
rpoB 760298 c.492G>C synonymous_variant 1.0
rpoB 760307 c.501T>C synonymous_variant 1.0
rpoB 760310 c.504G>C synonymous_variant 1.0
rpoB 760313 c.507G>C synonymous_variant 1.0
rpoB 760316 c.510C>G synonymous_variant 1.0
rpoB 760325 c.519G>C synonymous_variant 1.0
rpoB 760328 c.522G>C synonymous_variant 1.0
rpoB 760331 c.525G>T synonymous_variant 1.0
rpoB 760340 c.534G>T synonymous_variant 1.0
rpoB 760634 c.828T>C synonymous_variant 1.0
rpoB 760646 c.840C>G synonymous_variant 1.0
rpoB 760649 c.843G>C synonymous_variant 1.0
rpoB 760655 c.849A>G synonymous_variant 1.0
rpoB 760661 c.855A>C synonymous_variant 1.0
rpoB 760670 c.864G>C synonymous_variant 1.0
rpoB 760674 c.868T>C synonymous_variant 1.0
rpoB 760679 c.873A>G synonymous_variant 1.0
rpoB 760683 c.877T>C synonymous_variant 1.0
rpoB 761984 c.2178G>A synonymous_variant 1.0
rpoB 761999 c.2193G>C synonymous_variant 1.0
rpoB 762000 c.2194_2195delTCinsAG synonymous_variant 1.0
rpoB 762008 c.2202C>T synonymous_variant 1.0
rpoB 762047 c.2241G>A synonymous_variant 1.0
rpoB 762245 c.2439G>C synonymous_variant 1.0
rpoB 762266 c.2460T>C synonymous_variant 1.0
rpoB 762284 c.2478G>C synonymous_variant 1.0
rpoC 762929 c.-441G>T upstream_gene_variant 1.0
rpoC 762947 c.-423C>G upstream_gene_variant 1.0
rpoC 762962 c.-408C>T upstream_gene_variant 1.0
rpoC 762983 c.-387C>T upstream_gene_variant 1.0
rpoC 762989 c.-381G>T upstream_gene_variant 1.0
rpoC 762995 c.-375G>C upstream_gene_variant 1.0
rpoC 763028 c.-342T>C upstream_gene_variant 1.0
rpoC 763031 c.-339T>G upstream_gene_variant 1.0
rpoC 763040 c.-330C>G upstream_gene_variant 1.0
rpoC 763053 c.-317T>C upstream_gene_variant 1.0
rpoC 763058 c.-312C>G upstream_gene_variant 1.0
rpoC 763070 c.-300T>C upstream_gene_variant 1.0
rpoC 763082 c.-288C>G upstream_gene_variant 1.0
rpoC 763103 c.-267G>C upstream_gene_variant 1.0
rpoC 763115 c.-255T>C upstream_gene_variant 1.0
rpoC 763127 c.-243G>C upstream_gene_variant 1.0
rpoC 763142 c.-228C>G upstream_gene_variant 1.0
rpoC 763160 c.-210G>T upstream_gene_variant 1.0
rpoC 765405 p.Leu679Arg missense_variant 1.0
rpoC 765409 c.2040T>C synonymous_variant 1.0
rpoC 765454 c.2085C>G synonymous_variant 1.0
rpoC 765466 c.2097C>T synonymous_variant 1.0
rpoC 765478 c.2109T>C synonymous_variant 1.0
rpoC 765499 c.2130C>A synonymous_variant 1.0
rpoC 765533 p.Tyr722His missense_variant 1.0
rpoC 766321 c.2952C>G synonymous_variant 1.0
rpoC 766345 c.2976T>C synonymous_variant 1.0
rpoC 766348 c.2979A>G synonymous_variant 1.0
rpoC 766369 c.3000C>G synonymous_variant 1.0
rpoC 766381 c.3012C>T synonymous_variant 1.0
rpoC 766384 c.3015A>G synonymous_variant 1.0
rpoC 766393 c.3024C>G synonymous_variant 1.0
mmpL5 776027 c.2454G>C synonymous_variant 1.0
mmpL5 776039 c.2442C>A synonymous_variant 1.0
rplC 800678 c.-131C>T upstream_gene_variant 1.0
rplC 800693 c.-116A>G upstream_gene_variant 1.0
rplC 800703 c.-106T>C upstream_gene_variant 1.0
rpsA 1833847 c.306C>G synonymous_variant 1.0
rpsA 1833856 c.315A>G synonymous_variant 1.0
rpsA 1833874 c.333T>C synonymous_variant 1.0
rpsA 1833892 c.351G>A synonymous_variant 1.0
rpsA 1833894 p.Ala118Glu missense_variant 1.0
rpsA 1833928 c.387G>C synonymous_variant 1.0
rpsA 1833970 c.429G>T synonymous_variant 1.0
rpsA 1833979 c.438T>C synonymous_variant 1.0
rpsA 1833991 c.450C>A synonymous_variant 1.0
rpsA 1833994 c.453G>A synonymous_variant 1.0
rpsA 1834012 c.471G>T synonymous_variant 1.0
rpsA 1834015 c.474G>C synonymous_variant 1.0
rpsA 1834021 c.480C>T synonymous_variant 1.0
rpsA 1834030 c.489C>G synonymous_variant 1.0
rpsA 1834069 c.528G>C synonymous_variant 1.0
rpsA 1834396 c.855G>T synonymous_variant 1.0
rpsA 1834408 c.867C>G synonymous_variant 1.0
rpsA 1834411 c.870T>C synonymous_variant 1.0
rpsA 1834414 c.873C>T synonymous_variant 1.0
rpsA 1834423 c.882G>T synonymous_variant 1.0
katG 2155632 c.480A>C synonymous_variant 1.0
katG 2155635 c.477C>T synonymous_variant 1.0
rpoA 3877638 c.870T>C synonymous_variant 1.0
rpoA 3877656 c.852T>G synonymous_variant 1.0
rpoA 3877668 c.840A>G synonymous_variant 1.0
rpoA 3877671 c.837C>G synonymous_variant 1.0
rpoA 3877677 c.831G>C synonymous_variant 1.0
rpoA 3877686 c.822A>G synonymous_variant 1.0
rpoA 3877704 c.804G>T synonymous_variant 1.0
clpC1 4038578 c.2127C>T synonymous_variant 1.0
clpC1 4038587 c.2118C>T synonymous_variant 1.0
clpC1 4038596 c.2109A>G synonymous_variant 1.0
clpC1 4038605 c.2100G>A synonymous_variant 1.0
clpC1 4038613 p.Asn698His missense_variant 1.0
clpC1 4038614 c.2091C>T synonymous_variant 1.0
clpC1 4038623 c.2082A>G synonymous_variant 1.0
clpC1 4039589 c.1116G>C synonymous_variant 1.0
clpC1 4039592 c.1113G>C synonymous_variant 1.0
clpC1 4039610 c.1095G>C synonymous_variant 1.0
clpC1 4039622 c.1083C>T synonymous_variant 1.0
clpC1 4039649 c.1056G>C synonymous_variant 1.0
clpC1 4039652 c.1053G>C synonymous_variant 1.0
clpC1 4039661 c.1044T>C synonymous_variant 1.0
clpC1 4039670 c.1035G>C synonymous_variant 1.0
clpC1 4039904 c.801A>G synonymous_variant 1.0
clpC1 4039931 c.774T>C synonymous_variant 1.0
clpC1 4039937 c.768G>C synonymous_variant 1.0
clpC1 4039942 c.763C>T synonymous_variant 1.0
clpC1 4039946 c.759A>C synonymous_variant 1.0
clpC1 4039949 c.756G>C synonymous_variant 1.0
clpC1 4039952 c.753T>C synonymous_variant 1.0
clpC1 4039955 c.750G>C synonymous_variant 1.0
clpC1 4039958 c.747G>C synonymous_variant 1.0
clpC1 4040450 c.255A>G synonymous_variant 1.0
clpC1 4040456 c.249C>G synonymous_variant 1.0
clpC1 4040459 c.246C>G synonymous_variant 1.0
clpC1 4040465 c.240T>C synonymous_variant 1.0
clpC1 4040468 c.237G>C synonymous_variant 1.0
clpC1 4040471 c.234T>C synonymous_variant 1.0
clpC1 4040480 c.225T>C synonymous_variant 1.0
clpC1 4040501 c.204C>G synonymous_variant 1.0
clpC1 4040606 c.99T>C synonymous_variant 1.0
clpC1 4040644 c.61A>C synonymous_variant 1.0
clpC1 4040654 c.51G>A synonymous_variant 1.0
clpC1 4040669 c.36C>T synonymous_variant 1.0
clpC1 4040674 c.31A>C synonymous_variant 1.0
clpC1 4040675 c.30C>T synonymous_variant 1.0
clpC1 4040678 c.27C>A synonymous_variant 1.0
clpC1 4040690 c.15T>C synonymous_variant 1.0
clpC1 4040695 c.10C>A synonymous_variant 1.0
embC 4240819 c.957A>C synonymous_variant 1.0
embC 4240831 c.969T>G synonymous_variant 1.0
embC 4240852 c.990G>C synonymous_variant 1.0
embC 4240855 c.993G>T synonymous_variant 1.0
embC 4240867 c.1005T>G synonymous_variant 1.0
embC 4240870 c.1008T>C synonymous_variant 1.0