TB-Profiler result

Run: SRR6046395
Summary

Run ID: SRR6046395

Sample name:

Date: 04-04-2023 12:15:49

Number of reads: 15498

Percentage reads mapped: 1.65

Strain: lineage4.9

Drug-resistance: HR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
katG 2155693 p.Ser140Asn missense_variant 1.0 isoniazid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 1.0
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 1.0
rrs 1472240 n.395G>C non_coding_transcript_exon_variant 1.0
rrs 1472242 n.397C>T non_coding_transcript_exon_variant 1.0
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 1.0
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 1.0
rrs 1472264 n.419T>C non_coding_transcript_exon_variant 1.0
rrs 1472266 n.421C>A non_coding_transcript_exon_variant 1.0
rrl 1476336 n.2679C>G non_coding_transcript_exon_variant 1.0
rrl 1476356 n.2699C>G non_coding_transcript_exon_variant 1.0
rrl 1476357 n.2700T>A non_coding_transcript_exon_variant 1.0
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 1.0
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 1.0
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 1.0
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 1.0
rrl 1476384 n.2727G>C non_coding_transcript_exon_variant 1.0
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 1.0
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 1.0
rrl 1476428 n.2771C>A non_coding_transcript_exon_variant 1.0
rrl 1476443 n.2786G>C non_coding_transcript_exon_variant 1.0
rrl 1476455 n.2798C>G non_coding_transcript_exon_variant 1.0
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 1.0
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 1.0
rrl 1476470 n.2813C>T non_coding_transcript_exon_variant 1.0
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 1.0
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 1.0
katG 2155600 p.Cys171Val missense_variant 1.0
katG 2155613 p.Phe167Leu missense_variant 1.0
katG 2155614 c.498T>C synonymous_variant 1.0
katG 2155617 p.Ile165Met missense_variant 1.0
katG 2155626 c.486G>C synonymous_variant 1.0
katG 2155637 p.Leu159Ile missense_variant 1.0
katG 2155641 p.Lys157Arg missense_variant 1.0
katG 2155650 c.462G>A synonymous_variant 1.0
katG 2155655 p.Lys153Gln missense_variant 1.0
katG 2155661 p.Val151Ile missense_variant 1.0
katG 2155668 c.444G>C synonymous_variant 1.0
katG 2155689 c.421_423delTTGinsCTC synonymous_variant 1.0
katG 2155704 c.408C>T synonymous_variant 1.0
katG 2155716 c.396T>C synonymous_variant 1.0
katG 2155722 c.390G>C synonymous_variant 1.0
katG 2155728 c.384G>C synonymous_variant 1.0
katG 2155735 p.Met126Gln missense_variant 1.0
katG 2155737 c.375C>T synonymous_variant 1.0
katG 2155741 p.Gly124Ala missense_variant 1.0
katG 2155743 c.369G>T synonymous_variant 1.0
katG 2155765 p.His116Thr missense_variant 1.0
katG 2155782 c.330C>G synonymous_variant 1.0
katG 2155785 p.Ala109Ser missense_variant 1.0
katG 2155794 c.318G>C synonymous_variant 1.0