TB-Profiler result

Run: SRR6046781
Summary

Run ID: SRR6046781

Sample name:

Date: 04-04-2023 12:23:13

Number of reads: 96137

Percentage reads mapped: 11.3

Strain: lineage2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 0.14
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490654 c.-129G>T upstream_gene_variant 0.5
fgd1 491207 p.Leu142Gln missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575907 p.Ala187Val missense_variant 1.0
ccsA 620625 p.Ile245Met missense_variant 1.0
rpoB 760211 c.405C>T synonymous_variant 0.4
rpoC 764586 p.Leu406Pro missense_variant 0.5
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776182 p.Asp767Asn missense_variant 1.0
mmpR5 779447 p.Ala153Asp missense_variant 0.5
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0
rplC 800803 c.-6A>G upstream_gene_variant 0.33
fbiC 1302896 c.-35C>T upstream_gene_variant 0.29
Rv1258c 1406760 c.580_581insC frameshift_variant 1.0
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 1.0
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 1.0
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 1.0
ndh 2101723 c.1320G>A synonymous_variant 0.5
ndh 2102872 c.171A>G synonymous_variant 0.33
ndh 2102893 c.150G>C synonymous_variant 0.5
ndh 2102899 c.144T>C synonymous_variant 0.67
ndh 2102902 c.141C>G synonymous_variant 0.67
ndh 2102911 c.132G>C synonymous_variant 0.67
ndh 2102920 c.123G>A synonymous_variant 0.5
ndh 2102929 c.114T>C synonymous_variant 0.5
ndh 2102934 p.Asp37Asn missense_variant 0.5
ndh 2102938 p.Arg35His missense_variant 0.5
ndh 2102947 c.96G>A synonymous_variant 0.67
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2168059 p.Gln852Lys missense_variant 0.4
PPE35 2168891 c.1722A>G synonymous_variant 0.33
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518675 p.Met187Ile missense_variant 0.67
ribD 2987195 c.357C>A synonymous_variant 0.5
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473914 c.-93G>T upstream_gene_variant 0.33
fprA 3474687 c.681G>T synonymous_variant 0.33
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0
Rv3236c 3613057 c.60G>T synonymous_variant 0.18
ddn 3986869 p.Leu9Pro missense_variant 0.33
embA 4245811 p.Pro860Gln missense_variant 0.67
embA 4245812 c.2584delC frameshift_variant 0.67
embB 4247259 p.Ala249Asp missense_variant 0.29
embB 4247939 p.Leu476Met missense_variant 0.5
embB 4249301 p.Arg930Cys missense_variant 0.5
embB 4249498 c.2985G>A synonymous_variant 1.0
embB 4249668 c.3158_3162dupTGTCC frameshift_variant 0.67
aftB 4267137 p.Gln567Leu missense_variant 0.33
aftB 4267647 p.Asp397Gly missense_variant 1.0
ubiA 4269391 p.Val148Ala missense_variant 1.0
ethA 4326607 p.Trp289Cys missense_variant 0.2
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407927 p.Glu92Asp missense_variant 1.0