TB-Profiler result

Run: SRR6046907
Summary

Run ID: SRR6046907

Sample name:

Date: 04-04-2023 12:25:19

Number of reads: 20303

Percentage reads mapped: 38.89

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 1.0 kanamycin, capreomycin, aminoglycosides, amikacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5217 c.-23C>A upstream_gene_variant 1.0
gyrA 8869 p.Thr523Lys missense_variant 1.0
mshA 576757 c.1410C>A synonymous_variant 1.0
ccsA 620748 c.858T>G synonymous_variant 0.5
Rv1258c 1406245 c.1096C>T synonymous_variant 1.0
rrs 1472623 n.778A>C non_coding_transcript_exon_variant 1.0
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.5
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.67
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.67
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.67
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.67
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.67
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.67
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.75
rrs 1472767 n.922G>C non_coding_transcript_exon_variant 0.67
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 1.0
rrs 1472812 n.967A>T non_coding_transcript_exon_variant 1.0
rrs 1472911 n.1066T>C non_coding_transcript_exon_variant 1.0
rrs 1472915 n.1070G>A non_coding_transcript_exon_variant 1.0
rrs 1472918 n.1073A>G non_coding_transcript_exon_variant 1.0
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0
rrs 1473288 n.1443C>G non_coding_transcript_exon_variant 1.0
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 1.0
rrs 1473292 n.1447G>T non_coding_transcript_exon_variant 1.0
rrs 1473294 n.1449A>G non_coding_transcript_exon_variant 1.0
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 1.0
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 1.0
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 1.0
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 1.0
rrs 1473324 n.1479G>A non_coding_transcript_exon_variant 1.0
rrl 1474133 n.476T>A non_coding_transcript_exon_variant 1.0
rrl 1474141 n.484G>C non_coding_transcript_exon_variant 1.0
rrl 1474142 n.485C>G non_coding_transcript_exon_variant 1.0
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0
rrl 1474155 n.498G>A non_coding_transcript_exon_variant 1.0
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 1.0
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 1.0
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 1.0
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 1.0
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 1.0
rrl 1474186 n.529A>T non_coding_transcript_exon_variant 1.0
rrl 1474202 n.545T>C non_coding_transcript_exon_variant 1.0
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 1.0
rrl 1474582 n.925T>A non_coding_transcript_exon_variant 1.0
rrl 1475869 n.2212C>A non_coding_transcript_exon_variant 0.67
rrl 1475877 n.2220C>T non_coding_transcript_exon_variant 0.5
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.5
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.5
rrl 1475892 n.2235A>C non_coding_transcript_exon_variant 0.67
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.5
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.5
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.5
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 1.0
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 1.0
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 1.0
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 1.0
rrl 1476363 n.2706A>G non_coding_transcript_exon_variant 1.0
rrl 1476366 n.2709A>C non_coding_transcript_exon_variant 1.0
rrl 1476368 n.2711T>C non_coding_transcript_exon_variant 1.0
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 1.0
rrl 1476374 n.2717T>G non_coding_transcript_exon_variant 1.0
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 1.0
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 1.0
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 1.0
Rv2752c 3066278 c.-87C>A upstream_gene_variant 1.0
embC 4241330 p.Asp490Asn missense_variant 0.5
embC 4242118 c.2256C>G synonymous_variant 1.0
embA 4243460 c.228C>T synonymous_variant 1.0
aftB 4268084 c.753G>A synonymous_variant 1.0
ethA 4327325 p.Tyr50Phe missense_variant 1.0
ethA 4328338 c.-865G>A upstream_gene_variant 1.0