TB-Profiler result

Run: SRR6152717
Summary

Run ID: SRR6152717

Sample name:

Date: 2024-05-22T08:07:06.179183

Number of reads: 193291

Percentage reads mapped: 98.53

Median coverage: 4.0

Strain:

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage1.2.1.2 Indo-Oceanic RD239 0.17
lineage1.2.1.2.1 Indo-Oceanic RD239 0.1
lineage1.2.1 Indo-Oceanic RD239 0.22
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 1302 c.1302C>A synonymous_variant 0.87 isoniazid Not assoc w R
gyrA 7585 p.Ser95Thr missense_variant 0.92 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
nusG 734116 c.-138T>C upstream_gene_variant 0.85 rifampicin Not assoc w R
rpoC 763886 c.517C>A synonymous_variant 0.73 rifampicin Not assoc w R
whiB7 3568488 c.191delG frameshift_variant 0.8 streptomycin Uncertain significance
amikacin Uncertain significance
kanamycin Uncertain significance