TB-Profiler result

Run: SRR6479543
Summary

Run ID: SRR6479543

Sample name:

Date: 04-04-2023 14:32:46

Number of reads: 1669713

Percentage reads mapped: 99.81

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
pncA 2288751 c.489_490delGT frameshift_variant 0.18 pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1476232 n.2575G>T non_coding_transcript_exon_variant 0.18
fabG1 1673954 p.Ser172Trp missense_variant 0.1
PPE35 2169736 p.Gly293Ser missense_variant 0.18
PPE35 2169867 p.Ser249* stop_gained 0.14
embC 4241836 c.1974A>G synonymous_variant 0.13
embA 4244843 c.1611G>T synonymous_variant 0.13