TB-Profiler result

Run: SRR6484884
Summary

Run ID: SRR6484884

Sample name:

Date: 04-04-2023 14:50:35

Number of reads: 2150703

Percentage reads mapped: 99.81

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5857 c.618C>T synonymous_variant 0.43
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.25
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472642 n.797C>A non_coding_transcript_exon_variant 0.24
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
fabG1 1673380 c.-60C>G upstream_gene_variant 0.1
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169029 p.Asp528Glu missense_variant 0.29
PPE35 2169063 p.Met517Lys missense_variant 0.25
PPE35 2170048 p.Leu189Val missense_variant 0.12
PPE35 2170053 p.Thr187Ser missense_variant 0.11
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
clpC1 4040605 p.Leu34Ile missense_variant 0.24
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4248307 c.1794G>A synonymous_variant 1.0
ubiA 4269059 p.Ile259Val missense_variant 1.0
ethR 4327787 p.Val80Gly missense_variant 0.14
ethA 4328025 c.-552T>G upstream_gene_variant 0.23
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0