TB-Profiler result

Run: SRR6650187
Summary

Run ID: SRR6650187

Sample name:

Date: 04-04-2023 15:18:36

Number of reads: 2480181

Percentage reads mapped: 99.77

Strain: lineage4.9

Drug-resistance: HR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
katG 2155168 p.Ser315Thr missense_variant 1.0 isoniazid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777206 c.1275A>G synonymous_variant 0.1
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 0.98
PPE35 2170066 p.Ala183Thr missense_variant 0.21
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2747698 c.-100T>G upstream_gene_variant 1.0
aftB 4268326 p.Phe171Leu missense_variant 1.0
whiB6 4338457 p.Thr22Lys missense_variant 1.0
whiB6 4338459 p.Met21Ile missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0