TB-Profiler result

Run: SRR6785424
Summary

Run ID: SRR6785424

Sample name:

Date: 04-04-2023 15:54:31

Number of reads: 2862218

Percentage reads mapped: 99.56

Strain: lineage4.6.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
lineage4.6.2 Euro-American T;LAM RD726 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8736 p.Val479Met missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576089 p.Ala254Gly missense_variant 0.32
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpR5 778298 c.-692C>T upstream_gene_variant 0.99
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471786 n.-60T>C upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519247 p.Pro378Leu missense_variant 0.98
pepQ 2859505 p.Ala305Val missense_variant 1.0
Rv2752c 3066196 c.-5C>G upstream_gene_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.14
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474745 p.Gln247Lys missense_variant 1.0
whiB7 3568660 p.Pro7Arg missense_variant 1.0
fbiA 3640381 c.-162T>C upstream_gene_variant 1.0
rpoA 3878654 c.-147A>G upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4242883 c.-350C>T upstream_gene_variant 1.0
embB 4246544 p.Thr11Pro missense_variant 0.19
embB 4246548 p.Pro12Gln missense_variant 0.23
embB 4246555 c.42G>C synonymous_variant 0.25
embB 4246556 p.Ala15Pro missense_variant 0.25
embB 4246584 p.Arg24Pro missense_variant 0.35
whiB6 4338595 c.-75delG upstream_gene_variant 1.0