TB-Profiler result

Run: SRR6797843
Summary

Run ID: SRR6797843

Sample name:

Date: 2024-04-15T08:48:52.347529

Number of reads: 255544

Percentage reads mapped: 99.33

Median coverage: 5.0

Strain: lineage1.2.2.2

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage1.2.2 Indo-Oceanic RD239 0.31
lineage1.2.2.2 Indo-Oceanic RD239 1.0
lineage1 Indo-Oceanic RD239 0.49
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
mmpL5 777155 c.1326G>C synonymous_variant 0.9 clofazimine Not assoc w R - Interim
bedaquiline Not assoc w R - Interim
mtrB 3626268 p.Asp116Asn missense_variant 1.0 bedaquiline
rifampicin
embB 4247646 p.Glu378Ala missense_variant 1.0 ethambutol Not assoc w R