TB-Profiler result

Run: SRR6831725
Summary

Run ID: SRR6831725

Sample name:

Date: 04-04-2023 16:59:51

Number of reads: 580908

Percentage reads mapped: 99.65

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5077 c.-163_-162insC upstream_gene_variant 1.0
gyrA 6319 c.-983G>C upstream_gene_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 8391 p.Tyr364Asn missense_variant 0.22
fgd1 491338 p.Gly186Ser missense_variant 0.5
ccsA 619831 c.-60T>G upstream_gene_variant 0.4
rpoC 765820 c.2451G>A synonymous_variant 0.2
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1407316 p.Ala9Thr missense_variant 0.33
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472319 n.474C>G non_coding_transcript_exon_variant 0.29
rrs 1472608 n.767delG non_coding_transcript_exon_variant 0.17
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 0.4
fabG1 1673737 p.Met100Val missense_variant 0.4
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169258 p.Gln452Arg missense_variant 0.4
Rv1979c 2222027 p.Ile380Val missense_variant 0.4
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289080 c.162G>A synonymous_variant 0.18
folC 2746570 c.1029C>T synonymous_variant 0.29
fbiD 3339521 p.His135Leu missense_variant 0.2
rpoA 3878271 p.Asn79Lys missense_variant 0.14
clpC1 4038531 p.Glu725Val missense_variant 0.29
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246127 c.-387A>G upstream_gene_variant 0.2
embB 4248238 p.Met575Ile missense_variant 0.18
aftB 4267685 c.1152T>A synonymous_variant 0.4
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407689 c.513delA frameshift_variant 0.15