TB-Profiler result

Run: SRR6831983
Summary

Run ID: SRR6831983

Sample name:

Date: 04-04-2023 17:09:19

Number of reads: 492394

Percentage reads mapped: 99.65

Strain: lineage4.7

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6358 c.-944C>T upstream_gene_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7472 c.171T>C synonymous_variant 0.13
rpoB 760643 c.842delC frameshift_variant 0.13
rpoC 765126 p.Tyr586Ser missense_variant 0.29
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474294 n.637C>G non_coding_transcript_exon_variant 1.0
rrl 1475310 n.1653A>G non_coding_transcript_exon_variant 0.33
rpsA 1833874 c.333T>C synonymous_variant 0.18
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918193 p.Arg85His missense_variant 0.22
PPE35 2170244 c.369G>A synonymous_variant 0.22
Rv1979c 2222202 c.963C>T synonymous_variant 0.29
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
thyX 3067717 c.228delC frameshift_variant 0.2
Rv3083 3449125 p.Thr208Ser missense_variant 0.29
whiB7 3568727 c.-48T>A upstream_gene_variant 0.22
clpC1 4039125 p.Ala527Val missense_variant 0.2
clpC1 4039511 p.Lys398Asn missense_variant 0.12
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4249732 c.3219C>G synonymous_variant 1.0
aftB 4269456 c.-620G>T upstream_gene_variant 0.18
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407752 p.Pro151Ala missense_variant 0.18
gid 4407767 c.435delG frameshift_variant 0.18