TB-Profiler result

Run: SRR6832584
Summary

Run ID: SRR6832584

Sample name:

Date: 04-04-2023 17:31:01

Number of reads: 1621538

Percentage reads mapped: 99.64

Strain: lineage4.7

Drug-resistance: Other

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
gyrA 7582 p.Asp94Gly missense_variant 0.89 ofloxacin, moxifloxacin, levofloxacin, fluoroquinolones, ciprofloxacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6358 c.-944C>T upstream_gene_variant 0.97
gyrA 7362 p.Glu21Gln missense_variant 1.0
ccsA 619914 c.24C>A synonymous_variant 0.11
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpR5 779193 p.Ser68Arg missense_variant 0.11
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474294 n.637C>G non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168897 c.1716T>C synonymous_variant 0.1
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
clpC1 4038169 c.2531_2535delAGCCG frameshift_variant 0.12
clpC1 4038178 c.2526_2527insT frameshift_variant 0.12
clpC1 4038183 p.Gly841Ala missense_variant 0.12
panD 4044272 p.Thr4Ala missense_variant 0.12
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4249732 c.3219C>G synonymous_variant 1.0
aftB 4267640 c.1197C>A synonymous_variant 0.11
ethA 4326996 p.Pro160Ser missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0