TB-Profiler result

Run: SRR6855958
Summary

Run ID: SRR6855958

Sample name:

Date: 04-04-2023 17:51:14

Number of reads: 879190

Percentage reads mapped: 99.55

Strain: lineage4.8

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7569 p.Ala90Pro missense_variant 0.1
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 778468 p.Arg5Gly missense_variant 0.1
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303917 p.Met329Ile missense_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471820 n.-26T>C upstream_gene_variant 0.11
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1476634 n.2977T>C non_coding_transcript_exon_variant 0.11
inhA 1674565 p.Ile122Val missense_variant 0.1
tlyA 1917786 c.-153delA upstream_gene_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155323 c.789G>A synonymous_variant 0.14
PPE35 2168149 p.Pro822Ser missense_variant 1.0
PPE35 2169149 c.1464G>C synonymous_variant 1.0
PPE35 2170410 p.Ala68Val missense_variant 0.17
PPE35 2170554 p.Gly20Val missense_variant 0.2
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2746305 p.Thr432Ala missense_variant 0.11
folC 2747074 c.525G>T synonymous_variant 0.12
Rv3236c 3612056 p.Leu354* stop_gained 0.11
clpC1 4039729 p.Asp326Asn missense_variant 1.0
panD 4044439 c.-158G>T upstream_gene_variant 0.12
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244435 c.1203G>T synonymous_variant 0.11
embB 4246603 c.90C>A synonymous_variant 0.11
aftB 4267501 c.1333_1335delACC conservative_inframe_deletion 0.15
whiB6 4338595 c.-75delG upstream_gene_variant 1.0