TB-Profiler result

Run: SRR6896165
Summary

Run ID: SRR6896165

Sample name:

Date: 04-04-2023 17:57:33

Number of reads: 121353

Percentage reads mapped: 99.49

Strain:

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1.1.3 Euro-American (X-type) X1;X3 RD193 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6615 p.Glu459Gly missense_variant 0.33
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8826 p.Asp509His missense_variant 0.5
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
rpoC 766734 p.Leu1122Pro missense_variant 0.25
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303173 p.Arg81Ser missense_variant 0.18
atpE 1460850 c.-195C>T upstream_gene_variant 0.2
atpE 1460921 c.-124C>T upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673312 c.-128C>G upstream_gene_variant 0.29
fabG1 1673581 p.Gly48Arg missense_variant 0.22
inhA 1674582 p.Tyr127* stop_gained 0.5
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2288732 c.510C>T synonymous_variant 0.22
ribD 2986985 c.147G>A synonymous_variant 0.33
Rv2752c 3065260 p.Pro311Arg missense_variant 0.2
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087888 p.Thr357Ser missense_variant 0.29
fbiD 3339273 c.156T>G synonymous_variant 0.5
Rv3083 3448316 c.-188C>G upstream_gene_variant 0.4
Rv3083 3449933 p.Pro477Leu missense_variant 0.29
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474613 c.607C>T synonymous_variant 0.67
fbiB 3641812 p.Leu93Trp missense_variant 0.33
embC 4239901 c.39G>A synonymous_variant 0.12
embC 4242537 p.Asp892Gly missense_variant 0.33
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4249408 c.2895G>A synonymous_variant 1.0
aftB 4267082 c.1755C>T synonymous_variant 0.29
whiB6 4338193 p.Arg110Gln missense_variant 0.25
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407798 c.405G>T synonymous_variant 1.0