TB-Profiler result

Run: SRR6896486
Summary

Run ID: SRR6896486

Sample name:

Date: 04-04-2023 18:07:32

Number of reads: 126063

Percentage reads mapped: 98.39

Strain: lineage4

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
embC 4240724 p.Gly288Trp missense_variant 0.5 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6851 p.Gln538Lys missense_variant 0.4
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304806 p.Pro626Thr missense_variant 0.2
embR 1417250 p.Pro33His missense_variant 0.5
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
inhA 1674222 c.21C>A synonymous_variant 0.5
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102990 p.Val18Ala missense_variant 1.0
PPE35 2169840 p.Gly258Asp missense_variant 1.0
Rv1979c 2221863 p.Tyr434* stop_gained 0.22
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pepQ 2860502 c.-84A>T upstream_gene_variant 0.29
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3086921 c.102C>A synonymous_variant 0.17
ald 3087137 c.318G>A synonymous_variant 0.25
fbiD 3339690 c.573C>A synonymous_variant 0.25
Rv3083 3448608 c.105G>A synonymous_variant 1.0
Rv3083 3449625 p.Lys374Asn missense_variant 0.13
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612665 p.Val151Ala missense_variant 1.0
rpoA 3878403 c.105C>A synonymous_variant 0.33
clpC1 4039687 p.Arg340Ser missense_variant 0.4
clpC1 4040123 c.582G>A synonymous_variant 0.33
panD 4043940 c.342G>T synonymous_variant 0.18
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4269729 c.-893G>A upstream_gene_variant 0.29
ethA 4326818 p.Asp219Gly missense_variant 0.4
whiB6 4338595 c.-75delG upstream_gene_variant 1.0