TB-Profiler result

Run: SRR6896578
Summary

Run ID: SRR6896578

Sample name:

Date: 04-04-2023 18:10:28

Number of reads: 642214

Percentage reads mapped: 98.94

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7823 c.522G>T synonymous_variant 0.12
ccsA 620027 p.Pro46Gln missense_variant 0.14
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474625 n.968T>A non_coding_transcript_exon_variant 0.12
rrl 1476048 n.2391G>T non_coding_transcript_exon_variant 0.12
fabG1 1673323 c.-117C>A upstream_gene_variant 0.14
inhA 1674640 p.Met147Val missense_variant 0.13
tlyA 1917842 c.-98G>C upstream_gene_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2167674 p.Leu980Gln missense_variant 0.15
PPE35 2170046 c.567C>A synonymous_variant 0.13
PPE35 2170509 p.Ala35Val missense_variant 0.14
kasA 2518528 c.414C>A synonymous_variant 0.11
folC 2746870 p.Glu243Asp missense_variant 0.17
pepQ 2860000 p.Leu140Pro missense_variant 0.13
Rv2752c 3064574 p.Trp540Gly missense_variant 0.11
Rv2752c 3064850 p.Phe448Leu missense_variant 0.11
thyX 3068078 c.-133A>G upstream_gene_variant 0.12
fprA 3475304 p.Ala433Asp missense_variant 0.11
Rv3236c 3612515 p.Arg201His missense_variant 0.18
fbiA 3640472 c.-71G>C upstream_gene_variant 0.11
clpC1 4038251 p.Phe818Leu missense_variant 0.11
embC 4241554 c.1692G>T synonymous_variant 0.15
embA 4245397 p.Asn722Ser missense_variant 0.11
embB 4246250 c.-264G>T upstream_gene_variant 0.12
embB 4248654 p.Met714Thr missense_variant 0.11
embB 4249255 c.2742G>T synonymous_variant 0.11
whiB6 4338593 c.-73delT upstream_gene_variant 1.0
whiB6 4338596 c.-75G>C upstream_gene_variant 1.0