TB-Profiler result

Run: SRR6896588
Summary

Run ID: SRR6896588

Sample name:

Date: 04-04-2023 18:10:46

Number of reads: 1063966

Percentage reads mapped: 99.69

Strain: lineage4.7

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
fgd1 490751 c.-32T>G upstream_gene_variant 0.23
rpoB 759620 c.-187A>C upstream_gene_variant 0.28
rpoB 760957 p.Arg384Leu missense_variant 0.14
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781531 c.-29T>C upstream_gene_variant 0.11
fbiC 1303025 p.Arg32Leu missense_variant 0.17
Rv1258c 1407378 c.-38C>A upstream_gene_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472112 n.267C>A non_coding_transcript_exon_variant 0.22
rrl 1473430 n.-228G>T upstream_gene_variant 0.16
rrl 1473979 n.322G>T non_coding_transcript_exon_variant 0.22
rrl 1474115 n.458C>A non_coding_transcript_exon_variant 0.15
rrl 1474269 n.612C>A non_coding_transcript_exon_variant 0.2
rrl 1474287 n.630T>G non_coding_transcript_exon_variant 0.17
rrl 1474294 n.637C>G non_coding_transcript_exon_variant 1.0
rrl 1474975 n.1318G>C non_coding_transcript_exon_variant 0.14
rrl 1475162 n.1505G>A non_coding_transcript_exon_variant 1.0
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2101822 p.Phe407Leu missense_variant 0.14
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519168 p.Ala352Thr missense_variant 0.12
folC 2746612 c.987C>A synonymous_variant 0.14
fprA 3475340 p.Ala445Asp missense_variant 0.12
Rv3236c 3612898 c.219G>T synonymous_variant 0.16
embC 4242401 p.Arg847Ser missense_variant 0.2
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244751 p.Val507Met missense_variant 0.12
embA 4244850 c.1621delG frameshift_variant 0.2
embB 4246548 p.Pro12Gln missense_variant 0.14
embB 4246555 c.42G>C synonymous_variant 0.14
embB 4246556 p.Ala15Pro missense_variant 0.14
embB 4249732 c.3219C>G synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0