TB-Profiler result

Run: SRR6982032
Summary

Run ID: SRR6982032

Sample name:

Date: 04-04-2023 18:25:20

Number of reads: 733655

Percentage reads mapped: 99.29

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 0.97
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576767 p.Pro474Ser missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406320 p.Ala341Thr missense_variant 0.85
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.95
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 0.14
whiB7 3568744 c.-65A>G upstream_gene_variant 1.0
whiB7 3568745 c.-66C>G upstream_gene_variant 1.0
Rv3236c 3612481 p.His212Gln missense_variant 0.11
embC 4240001 p.Thr47Ser missense_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4245945 p.Ile905Val missense_variant 0.13
aftB 4268536 p.Gly101Trp missense_variant 0.15
aftB 4268794 p.Val15Met missense_variant 1.0
ubiA 4269906 c.-73G>T upstream_gene_variant 0.12
ethR 4328036 p.Pro163Leu missense_variant 0.92
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0