TB-Profiler result

Run: SRR6982085
Summary

Run ID: SRR6982085

Sample name:

Date: 04-04-2023 18:26:51

Number of reads: 587784

Percentage reads mapped: 99.1

Strain: lineage4.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
ccsA 619940 p.Ala17Val missense_variant 0.12
ccsA 620319 c.429C>T synonymous_variant 0.12
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpR5 779125 p.Cys46Arg missense_variant 0.12
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2714422 p.Ala304Val missense_variant 1.0
pepQ 2859482 p.Ala313Thr missense_variant 0.11
pepQ 2860235 p.Thr62Ala missense_variant 0.1
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339645 c.528C>G synonymous_variant 0.13
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiA 3640651 p.Ala37Pro missense_variant 0.12
fbiA 3641447 p.Thr302Met missense_variant 1.0
alr 3840365 c.1056C>T synonymous_variant 0.12
rpoA 3877553 p.Glu319Lys missense_variant 1.0
embC 4240897 c.1035C>G synonymous_variant 0.94
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4243054 c.-179G>A upstream_gene_variant 0.12
embB 4247484 p.Gly324Asp missense_variant 0.11
embB 4247670 p.Ala386Glu missense_variant 1.0
embB 4249408 c.2895G>A synonymous_variant 0.85
aftB 4267091 c.1746C>A synonymous_variant 0.13
aftB 4267351 p.Met496Leu missense_variant 0.12
aftB 4267603 p.Arg412Gly missense_variant 0.13
aftB 4268620 p.Val73Leu missense_variant 0.33
whiB6 4338595 c.-75delG upstream_gene_variant 1.0