TB-Profiler result

Run: SRR6982336
Summary

Run ID: SRR6982336

Sample name:

Date: 04-04-2023 18:34:32

Number of reads: 712893

Percentage reads mapped: 99.79

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 7182 p.Phe648Ser missense_variant 0.1
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 9808 p.Thr836Lys missense_variant 1.0
mshA 575701 p.Glu118Asp missense_variant 0.11
rpoB 760736 c.930C>T synonymous_variant 0.11
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
fbiC 1304268 c.1338G>C synonymous_variant 0.1
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1475187 n.1530C>T non_coding_transcript_exon_variant 0.14
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2103007 c.35delC frameshift_variant 0.1
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289728 c.-487A>G upstream_gene_variant 0.11
pncA 2290010 c.-769G>T upstream_gene_variant 0.15
Rv3236c 3612424 c.693G>T synonymous_variant 0.15
fbiB 3642611 c.1077C>T synonymous_variant 0.11
fbiB 3642694 c.1163_1166dupTGGC frameshift_variant 0.12
embC 4242528 p.Gly889Glu missense_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4245551 c.2322delC frameshift_variant 0.12
aftB 4266958 p.Glu627* stop_gained 0.1
aftB 4267121 c.1716G>T synonymous_variant 0.11
aftB 4267550 p.Tyr429* stop_gained 0.12
ubiA 4269575 c.258delC frameshift_variant 0.12
whiB6 4338592 c.-71G>C upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0