TB-Profiler result

Run: SRR833187
Summary

Run ID: SRR833187

Sample name:

Date: 04-04-2023 21:15:14

Number of reads: 350356

Percentage reads mapped: 87.92

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 8035 p.Lys245Thr missense_variant 0.25
rpoB 759794 c.-13G>T upstream_gene_variant 0.33
rpoB 760153 c.351_356delAGACAA disruptive_inframe_deletion 0.15
rpoB 761298 p.Ala498Thr missense_variant 0.67
rpoC 766656 p.Glu1096Gly missense_variant 0.4
rpoC 766687 p.Glu1106Asp missense_variant 0.29
mmpS5 778562 p.Arg115Leu missense_variant 0.5
embR 1417547 c.-200A>C upstream_gene_variant 0.22
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673560 p.Lys41Gln missense_variant 0.67
ndh 2102751 p.Cys98Arg missense_variant 0.17
katG 2156058 p.Asn18Met missense_variant 0.13
PPE35 2168612 c.2001C>T synonymous_variant 0.17
PPE35 2169320 p.Leu431Phe missense_variant 0.44
Rv1979c 2222397 c.768A>C synonymous_variant 0.67
kasA 2518302 p.His63Arg missense_variant 0.17
kasA 2519162 p.Val350Ile missense_variant 1.0
pepQ 2860400 p.Arg7* stop_gained 0.22
ribD 2987103 c.266delG frameshift_variant 0.5
ribD 2987137 p.Val100Gly missense_variant 0.67
Rv2752c 3065830 p.Ile121Arg missense_variant 0.25
thyA 3074076 c.396C>G synonymous_variant 0.4
Rv3083 3449465 p.Ile321Asn missense_variant 0.25
alr 3840233 c.1188A>C synonymous_variant 0.25
clpC1 4040749 c.-45T>C upstream_gene_variant 0.15
panD 4044142 p.Val47Ala missense_variant 0.13
embC 4241340 p.Phe493Cys missense_variant 0.4
embA 4244659 p.Leu476Pro missense_variant 0.33
embA 4245046 p.Leu605Pro missense_variant 0.15
embB 4248085 c.1572T>C synonymous_variant 0.25
ubiA 4269781 p.Val18Gly missense_variant 0.5
ethA 4326235 c.1239T>G synonymous_variant 0.15