TB-Profiler result

Run: SRR8791310
Summary

Run ID: SRR8791310

Sample name:

Date: 18-08-2022 12:19:56

Number of reads: 655134

Percentage reads mapped: 99.5

Strain:

Drug-resistance: Pre-XDR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
gyrA 7582 p.Asp94Ala missense_variant 1.0 ofloxacin, moxifloxacin, levofloxacin, fluoroquinolones, ciprofloxacin
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
fabG1 1673432 c.-8T>G upstream_gene_variant 1.0 isoniazid
pncA 2288818 p.Thr142Pro missense_variant 1.0 pyrazinamide
pncA 2289105 c.136delG frameshift_variant 0.14 pyrazinamide
eis 2715344 c.-12C>T upstream_gene_variant 1.0 kanamycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7791 p.Thr164Pro missense_variant 0.2