TB-Profiler result

Run: SRR9613540
Summary

Run ID: SRR9613540

Sample name:

Date: 04-04-2023 22:54:05

Number of reads: 4515312

Percentage reads mapped: 99.99

Strain: lineage4.6.2.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 0.98
lineage4.6.2 Euro-American T;LAM RD726 0.99
lineage4.6.2.2 Euro-American (Cameroon) LAM10-CAM RD726 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 0.98
mmpR5 778298 c.-692C>T upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.22
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.22
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.22
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.29
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.22
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.2
rrs 1473128 n.1283C>T non_coding_transcript_exon_variant 0.15
rrl 1473717 n.60G>T non_coding_transcript_exon_variant 0.16
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.12
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.16
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 0.15
rrl 1474878 n.1221C>T non_coding_transcript_exon_variant 0.18
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.15
rrl 1475003 n.1346G>A non_coding_transcript_exon_variant 0.2
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.14
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.13
rrl 1475754 n.2097G>A non_coding_transcript_exon_variant 0.14
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.15
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.15
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.15
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.17
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 0.14
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.14
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.18
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 0.17
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 0.17
inhA 1673393 c.-809G>C upstream_gene_variant 0.98
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2221746 c.1416_1418dupCCG disruptive_inframe_insertion 0.91
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2746320 p.Pro427Ala missense_variant 0.99
Rv3083 3448567 p.His22Asp missense_variant 0.96
fprA 3473996 c.-11_-10insA upstream_gene_variant 0.98
rpoA 3878599 c.-92C>G upstream_gene_variant 0.11
ddn 3987011 c.168C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4267272 p.Lys522Arg missense_variant 1.0
ethR 4326739 c.-810G>C upstream_gene_variant 0.97
ethA 4328004 c.-531C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0