TB-Profiler result

Run: SRR9613543
Summary

Run ID: SRR9613543

Sample name:

Date: 04-04-2023 22:54:12

Number of reads: 2892861

Percentage reads mapped: 99.9

Strain: lineage4.5

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.5 Euro-American H;T RD122 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7892 c.591G>A synonymous_variant 1.0
gyrA 9236 c.1935G>T synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
ccsA 620029 c.139C>T synonymous_variant 1.0
rpoC 764743 c.1374G>A synonymous_variant 1.0
rpoC 766789 c.3420G>A synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1416481 c.867G>A synonymous_variant 0.71
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472452 n.607G>T non_coding_transcript_exon_variant 0.95
rrl 1474425 n.768A>G non_coding_transcript_exon_variant 0.14
rrl 1474428 n.771C>T non_coding_transcript_exon_variant 0.14
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170568 p.Ile15Met missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2746984 c.615C>T synonymous_variant 1.0
thyA 3073868 p.Thr202Ala missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 0.98
rpoA 3878575 c.-68C>T upstream_gene_variant 1.0
clpC1 4038318 p.Pro796Leu missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0