TB-Profiler result

Run: SRR9940963
Summary

Run ID: SRR9940963

Sample name:

Date: 04-04-2023 23:01:33

Number of reads: 241379

Percentage reads mapped: 99.86

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6934 p.Gln565His missense_variant 0.29
gyrA 9416 p.Phe705Leu missense_variant 0.22
rpoB 759615 c.-192A>C upstream_gene_variant 0.22
rpoB 759620 c.-187A>C upstream_gene_variant 0.2
rpoB 762810 c.3006delC frameshift_variant 0.4
rpoC 764389 c.1020G>A synonymous_variant 0.67
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471894 n.49G>C non_coding_transcript_exon_variant 0.18
rrs 1472601 n.756G>T non_coding_transcript_exon_variant 0.2
fabG1 1673380 c.-60C>G upstream_gene_variant 0.2
ndh 2103222 c.-180A>G upstream_gene_variant 0.23
PPE35 2170598 c.15G>A synonymous_variant 1.0
Rv1979c 2222107 p.Phe353Ser missense_variant 0.17
ahpC 2725938 c.-255_-254insA upstream_gene_variant 0.4
fbiD 3339720 c.607dupG frameshift_variant 0.29
Rv3083 3449138 p.Arg212Leu missense_variant 0.67
Rv3083 3449667 c.1166dupG frameshift_variant 0.67
fprA 3474133 p.Pro43Thr missense_variant 0.33
whiB7 3568763 c.-84C>A upstream_gene_variant 0.25
Rv3236c 3612064 c.1053T>C synonymous_variant 0.2
Rv3236c 3612112 p.Glu335Asp missense_variant 0.18
fbiA 3640785 p.Gln81His missense_variant 0.4
fbiA 3640895 p.Met118Thr missense_variant 0.25
rpoA 3877996 p.Val171Ala missense_variant 0.4
ddn 3987077 c.234C>A synonymous_variant 0.4
clpC1 4040165 c.540G>C synonymous_variant 0.22
panD 4043912 c.369delT frameshift_variant 0.25
embC 4240630 c.768C>A synonymous_variant 0.4