TB-Profiler result

Run: SRR9940981
Summary

Run ID: SRR9940981

Sample name:

Date: 04-04-2023 23:02:01

Number of reads: 1194126

Percentage reads mapped: 99.44

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6927 p.Leu563Trp missense_variant 0.2
fgd1 491478 p.Lys232Asn missense_variant 0.12
rpoB 760178 c.372G>A synonymous_variant 0.12
rplC 801352 p.Val182Met missense_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.12
rrs 1473153 n.1308G>T non_coding_transcript_exon_variant 0.1
rrl 1475335 n.1678G>T non_coding_transcript_exon_variant 0.18
inhA 1674951 c.750G>T synonymous_variant 0.1
tlyA 1918719 c.780G>T synonymous_variant 0.11
PPE35 2170250 c.363G>T synonymous_variant 0.11
PPE35 2170598 c.15G>A synonymous_variant 1.0
PPE35 2170643 c.-31G>T upstream_gene_variant 0.1
Rv1979c 2222465 p.Gly234Cys missense_variant 0.11
kasA 2518151 p.Ser13Arg missense_variant 0.23
pepQ 2860063 c.355delA frameshift_variant 1.0
embC 4243033 p.Trp1057Cys missense_variant 0.11
embB 4248696 p.Arg728Leu missense_variant 0.18
aftB 4267725 p.Leu371Pro missense_variant 0.11