Variant selector
Mutations must follow the HGVS nomenclature. More info?
Mutations must follow the HGVS nomenclature. Information on this format can be found here.
The following types of mutations are currently allowed:
  • Amino acid substitutions: Example: S450L in rpoB would be p.Ser450Leu
  • Deletions in genes: Example: Deletion of nucleotide 758 in tlyA would be c.758del
  • Insertion in genes: Example: Insertion of GT between nucleotide 1850 and 1851 in katG would be c.1850_1851insGT
  • SNPs in non-coding RNAs: Example: A to G at position 1401 in rrs would be r.1401a>g
  • SNPs in gene promoters: Example: A to G 7 bases 5' of the start codon in pncA c.-7A>G
Important! The mutations and resulting library files are in reference to the H37Rv (NC_000962.3/AL123456.3) reference genome.