TB-Profiler result

Run: DRR034513
Summary

Run ID: DRR034513

Sample name:

Date: 31-03-2023 07:01:00

Number of reads: 803890

Percentage reads mapped: 99.31

Strain: lineage4.7

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1305494 c.2565_*55delGGCCTAGCCCCGGCGACGATGCCGGGTCGCGGGATGCGGCCCGTTGAGGAGCGGGGCAATCT frameshift_variant&stop_lost&splice_region_variant 0.29
Rv1258c 1406825 c.516C>T synonymous_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474294 n.637C>G non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170675 c.-63G>C upstream_gene_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2746216 p.Phe461Leu missense_variant 0.13
folC 2747498 p.Leu34Pro missense_variant 0.12
ribD 2986965 p.Ala43Thr missense_variant 0.15
ribD 2987323 p.Val162Gly missense_variant 0.22
Rv2752c 3067075 c.-884C>A upstream_gene_variant 1.0
Rv3083 3448672 p.Ser57Ala missense_variant 1.0
Rv3083 3449082 c.579T>A synonymous_variant 0.17
alr 3840224 c.1197C>T synonymous_variant 1.0
ddn 3987000 p.Gly53Ser missense_variant 0.97
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243931 c.699G>A synonymous_variant 0.17
embB 4249732 c.3219C>G synonymous_variant 1.0
aftB 4267400 c.1437G>T synonymous_variant 0.11
ubiA 4269861 c.-28G>A upstream_gene_variant 0.12
whiB6 4338527 c.-6T>C upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
fbiC 1305494 c.2565_*56delCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN frameshift_variant&stop_lost&splice_region_variant 1.0