TB-Profiler result

Run: DRR130239
Summary

Run ID: DRR130239

Sample name:

Date: 31-03-2023 07:11:17

Number of reads: 553709

Percentage reads mapped: 98.83

Strain: lineage4.2.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.2 Euro-American H;T;LAM None 1.0
lineage4.2.2 Euro-American (Ural) T;LAM7-TUR None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 7121 p.Pro628Ala missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576077 c.730C>T synonymous_variant 1.0
rpoC 766854 p.Leu1162Pro missense_variant 0.1
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2715411 c.-79A>G upstream_gene_variant 0.22
Rv2752c 3066280 c.-89C>T upstream_gene_variant 0.97
ald 3086742 c.-78A>C upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878569 c.-63_-62insG upstream_gene_variant 0.12
rpoA 3878580 c.-74_-73insCAACCCA upstream_gene_variant 0.11
clpC1 4038527 c.2178G>A synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244400 p.Leu390Met missense_variant 0.96
embA 4244899 p.Thr556Met missense_variant 0.12
embB 4249533 p.Ala1007Val missense_variant 0.96
whiB6 4338405 c.117T>C synonymous_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0