TB-Profiler result

Run: ERR023195
Summary

Run ID: ERR023195

Sample name:

Date: 31-03-2023 07:58:42

Number of reads: 5001501

Percentage reads mapped: 98.12

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
rpoB 759827 p.Ser7Arg missense_variant 0.22
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777504 p.Phe326Ser missense_variant 0.17
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1305402 c.2472C>T synonymous_variant 1.0
atpE 1460907 c.-138T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471746 n.-100G>T upstream_gene_variant 0.24
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1476154 n.2497G>T non_coding_transcript_exon_variant 0.26
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918058 p.Val40Gly missense_variant 0.26
PPE35 2168149 p.Pro822Ser missense_variant 0.98
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518146 p.Phe11Ser missense_variant 0.32
Rv2752c 3065697 c.495C>T synonymous_variant 0.98
Rv3083 3448490 c.-14A>C upstream_gene_variant 0.25
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
fprA 3475230 p.Asp408Glu missense_variant 1.0
rpoA 3878641 c.-135delG upstream_gene_variant 0.18
clpC1 4039729 p.Asp326Asn missense_variant 1.0
clpC1 4040093 c.612C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 0.98
embA 4243413 p.Pro61Ala missense_variant 0.98
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448497 c.-6_*1408del transcript_ablation 1.0