TB-Profiler result

Run: ERR023261
Summary

Run ID: ERR023261

Sample name:

Date: 31-03-2023 07:59:10

Number of reads: 8191491

Percentage reads mapped: 99.46

Strain: lineage4.5

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.5 Euro-American H;T RD122 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7892 c.591G>A synonymous_variant 0.99
gyrA 9304 p.Gly668Asp missense_variant 1.0
ccsA 620029 c.139C>T synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406101 p.Pro414Ser missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
inhA 1674819 c.618G>T synonymous_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 0.99
PPE35 2167859 c.2754T>G synonymous_variant 0.2
PPE35 2170568 p.Ile15Met missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 0.99
fbiB 3642772 p.Asp413Ala missense_variant 0.22
rpoA 3878575 c.-68C>T upstream_gene_variant 1.0
clpC1 4038240 p.Gly822Val missense_variant 0.32
clpC1 4038318 p.Pro796Leu missense_variant 1.0
clpC1 4038857 c.1848C>A synonymous_variant 0.35
clpC1 4039932 p.Gly258Val missense_variant 0.28
embC 4239842 c.-21C>A upstream_gene_variant 0.21
embC 4242425 p.Arg855Gly missense_variant 0.24
embC 4242476 p.Pro872Ala missense_variant 0.18
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242822 p.Val987Gly missense_variant 0.28
ubiA 4269529 p.Ala102Gly missense_variant 0.29
whiB6 4338595 c.-75delG upstream_gene_variant 1.0