TB-Profiler result

Run: ERR023735

Summary

Run ID: ERR023735

Sample name:

Date: 31-03-2023 08:01:18

Number of reads: 882112

Percentage reads mapped: 93.46

Strain: lineage4.7

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1473022 n.1177G>T non_coding_transcript_exon_variant 0.1
rrl 1474294 n.637C>G non_coding_transcript_exon_variant 1.0
inhA 1674952 p.Pro251Ala missense_variant 0.23
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102577 p.Glu156Lys missense_variant 0.1
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2726756 c.564C>T synonymous_variant 0.2
thyX 3067995 c.-50A>C upstream_gene_variant 0.15
alr 3841485 c.-65G>A upstream_gene_variant 0.1
clpC1 4039932 p.Gly258Val missense_variant 0.15
panD 4043878 c.403delC frameshift_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244286 p.Gly352Cys missense_variant 0.15
embB 4249732 c.3219C>G synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0