TB-Profiler result

Run: ERR024337
Summary

Run ID: ERR024337

Sample name:

Date: 31-03-2023 08:09:27

Number of reads: 1142065

Percentage reads mapped: 98.07

Strain: lineage4.3.2

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.2 Euro-American (LAM) LAM3 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoB 759707 c.-100C>A upstream_gene_variant 0.17
rpoB 761075 p.Glu423Asp missense_variant 0.11
rpoC 764995 c.1626C>G synonymous_variant 1.0
rpoC 765160 c.1791C>A synonymous_variant 0.11
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303016 p.Val29Gly missense_variant 0.14
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472337 n.492C>T non_coding_transcript_exon_variant 1.0
inhA 1674365 p.Pro55Arg missense_variant 0.11
inhA 1674952 p.Pro251Ala missense_variant 0.23
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518144 c.29dupG frameshift_variant 0.12
eis 2715424 c.-92C>G upstream_gene_variant 0.31
ahpC 2726338 p.Val49Gly missense_variant 0.47
thyA 3073868 p.Thr202Ala missense_variant 1.0
thyA 3074657 c.-186C>G upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiB 3642772 p.Asp413Ala missense_variant 0.33
clpC1 4038287 c.2418C>T synonymous_variant 1.0
embC 4239842 c.-21C>A upstream_gene_variant 0.18
embC 4240559 p.Ala233Ser missense_variant 0.2
embC 4240646 p.Phe262Val missense_variant 0.21
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4242883 c.-350C>G upstream_gene_variant 1.0
embA 4243705 p.Gly158Asp missense_variant 1.0
embA 4245543 p.Gly771Cys missense_variant 0.15
embB 4248706 c.2193G>A synonymous_variant 1.0
ubiA 4269529 p.Ala102Gly missense_variant 0.32
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407644 p.Arg187Trp missense_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0