TB-Profiler result

Run: ERR024341
Summary

Run ID: ERR024341

Sample name:

Date: 31-03-2023 08:10:27

Number of reads: 1233908

Percentage reads mapped: 95.71

Strain: lineage4.3.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.2 Euro-American (LAM) LAM3 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoB 761642 c.1836G>A synonymous_variant 0.12
rpoC 764352 p.Val328Gly missense_variant 0.22
rpoC 764995 c.1626C>G synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472337 n.492C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169320 p.Leu431Phe missense_variant 0.17
PPE35 2169862 p.Asn251His missense_variant 0.14
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518141 c.29dupG frameshift_variant 0.14
thyA 3073868 p.Thr202Ala missense_variant 1.0
thyA 3074657 c.-186C>G upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiB 3641955 p.Gly141Arg missense_variant 0.38
clpC1 4038287 c.2418C>T synonymous_variant 1.0
clpC1 4038857 c.1848C>A synonymous_variant 0.33
embC 4240411 c.549G>C synonymous_variant 0.17
embC 4240793 p.Ala311Pro missense_variant 0.1
embC 4242425 p.Arg855Gly missense_variant 0.2
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4242883 c.-350C>G upstream_gene_variant 1.0
embA 4243705 p.Gly158Asp missense_variant 1.0
embB 4248706 c.2193G>A synonymous_variant 1.0
ethA 4326677 p.Ser266Ile missense_variant 0.11
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407644 p.Arg187Trp missense_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0