TB-Profiler result

Run: ERR10112415
Summary

Run ID: ERR10112415

Sample name:

Date: 03-01-2024 01:57:33

Number of reads: 381950

Percentage reads mapped: 99.31

Strain: lineage4;lineage2.2.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Rifampicin
Isoniazid
Ethambutol
Pyrazinamide
Streptomycin
Fluoroquinolones
Moxifloxacin
Ofloxacin
Levofloxacin
Ciprofloxacin
Aminoglycosides
Amikacin
Capreomycin
Kanamycin
Cycloserine
Ethionamide
Clofazimine
Para-aminosalicylic_acid
Delamanid
Bedaquiline
Linezolid
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 0.2
lineage4 Euro-American LAM;T;S;X;H None 0.96
lineage2.2 East-Asian (Beijing) Beijing-RD207 RD105;RD207 0.31
lineage2.2.1 East-Asian (Beijing) Beijing-RD181 RD105;RD207;RD181 0.5
lineage2.2.1.1 East-Asian (Beijing) Beijing-RD150 RD105;RD207;RD181;RD150 0.18
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
eis 2714846 p.Val163Ile missense_variant 1.0
folC 2747575 c.24G>A synonymous_variant 0.43
pepQ 2859684 p.Trp245* stop_gained 0.4
embA 4242643 c.-590C>T upstream_gene_variant 1.0