TB-Profiler result

Run: ERR11043061

Summary

Run ID: ERR11043061

Sample name:

Date: 31-03-2023 11:27:11

Number of reads: 1640651

Percentage reads mapped: 99.92

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168237 c.2376G>T synonymous_variant 0.19
PPE35 2169013 p.Val534Leu missense_variant 0.23
PPE35 2170219 p.Ala132Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
thyA 3074139 c.333G>A synonymous_variant 1.0
rpoA 3877972 p.Asp179Ala missense_variant 1.0
rpoA 3878630 c.-123G>C upstream_gene_variant 0.16
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4268636 c.201G>A synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0