TB-Profiler result

Run: ERR11049474
Summary

Run ID: ERR11049474

Sample name:

Date: 01-04-2023 05:17:38

Number of reads: 6396738

Percentage reads mapped: 99.57

Strain: lineage4.5

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.5 Euro-American H;T RD122 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7892 c.591G>A synonymous_variant 1.0
gyrA 8155 p.Thr285Ile missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9647 c.2346C>G synonymous_variant 0.19
mshA 576113 p.Arg256Gly missense_variant 0.3
mshA 576616 c.1269G>C synonymous_variant 0.29
ccsA 620029 c.139C>T synonymous_variant 1.0
rpoC 764367 p.Gly333Ala missense_variant 0.21
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777883 p.Gly200Arg missense_variant 0.19
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406101 p.Pro414Ser missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.35
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.3
PPE35 2170568 p.Ile15Met missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519071 p.Asp319Glu missense_variant 0.27
Rv2752c 3064823 p.Val457Leu missense_variant 0.18
fbiD 3339734 p.Ala206Gly missense_variant 0.45
fbiD 3339749 p.Val211Gly missense_variant 0.3
fbiD 3339751 p.Ala212Pro missense_variant 0.22
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568425 c.255T>C synonymous_variant 0.27
whiB7 3568428 c.252A>G synonymous_variant 0.47
Rv3236c 3612267 p.Pro284Ala missense_variant 1.0
rpoA 3878575 c.-68C>T upstream_gene_variant 1.0
rpoA 3878597 c.-90G>C upstream_gene_variant 0.26
rpoA 3878609 c.-102T>G upstream_gene_variant 0.4
rpoA 3878613 c.-106A>C upstream_gene_variant 0.6
rpoA 3878618 c.-111A>C upstream_gene_variant 0.29
rpoA 3878639 c.-132C>G upstream_gene_variant 0.12
rpoA 3878641 c.-134C>G upstream_gene_variant 0.49
clpC1 4038318 p.Pro796Leu missense_variant 1.0
embC 4240409 p.Pro183Ala missense_variant 0.35
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246527 p.Ala5Gly missense_variant 0.27
embB 4246584 p.Arg24Pro missense_variant 0.15
embB 4247016 p.Ser168Trp missense_variant 0.3
embB 4247020 c.507C>G synonymous_variant 0.32
embB 4248328 c.1815G>C synonymous_variant 0.22
whiB6 4338205 p.Val106Gly missense_variant 0.21
whiB6 4338595 c.-75delG upstream_gene_variant 1.0