TB-Profiler result

Run: ERR11049645
Summary

Run ID: ERR11049645

Sample name:

Date: 01-04-2023 13:44:02

Number of reads: 2410600

Percentage reads mapped: 99.67

Strain: lineage4.7

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304749 p.Pro607Ala missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474294 n.637C>G non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.26
PPE35 2170675 c.-63G>C upstream_gene_variant 1.0
Rv1979c 2222497 p.Leu223Pro missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pepQ 2860159 p.Ala87Gly missense_variant 0.23
fbiD 3339734 p.Ala206Gly missense_variant 0.83
fbiD 3339746 p.Ala210Gly missense_variant 0.43
whiB7 3568797 c.-118G>T upstream_gene_variant 1.0
fbiB 3642275 c.741A>G synonymous_variant 1.0
rpoA 3878618 c.-111A>C upstream_gene_variant 0.33
rpoA 3878641 c.-134C>G upstream_gene_variant 0.45
embC 4240409 p.Pro183Ala missense_variant 0.18
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246527 p.Ala5Gly missense_variant 0.24
embB 4246529 p.Ser6Gly missense_variant 0.29
embB 4246584 p.Arg24Pro missense_variant 0.6
embB 4249732 c.3219C>G synonymous_variant 1.0
whiB6 4338205 p.Val106Gly missense_variant 0.27
whiB6 4338595 c.-75delG upstream_gene_variant 1.0