TB-Profiler result

Run: ERR11049796

Summary

Run ID: ERR11049796

Sample name:

Date: 01-04-2023 21:04:00

Number of reads: 1970814

Percentage reads mapped: 99.79

Strain: lineage4.8

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 8933 c.1632G>A synonymous_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.24
mshA 576616 c.1269G>C synonymous_variant 0.17
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776894 p.Ile529Met missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.21
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918107 c.168C>T synonymous_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.17
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519071 p.Asp319Glu missense_variant 0.19
pepQ 2860159 p.Ala87Gly missense_variant 0.2
fbiD 3339734 p.Ala206Gly missense_variant 0.64
fbiD 3339746 p.Ala210Gly missense_variant 0.25
rpoA 3878641 c.-134C>G upstream_gene_variant 0.33
embC 4240409 p.Pro183Ala missense_variant 0.11
embC 4242434 p.Val858Met missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246544 p.Thr11Pro missense_variant 0.25
embB 4246548 p.Pro12Gln missense_variant 0.22
embB 4246555 c.42G>C synonymous_variant 0.22
embB 4246556 p.Ala15Pro missense_variant 0.22
embB 4248328 c.1815G>C synonymous_variant 0.14
aftB 4267352 c.1485C>T synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0