TB-Profiler result

Run: ERR11050036
Summary

Run ID: ERR11050036

Sample name:

Date: 02-04-2023 08:42:50

Number of reads: 6539585

Percentage reads mapped: 99.48

Strain: lineage4.5

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.5 Euro-American H;T RD122 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7892 c.591G>A synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576442 p.Cys365Trp missense_variant 0.21
mshA 576616 c.1269G>C synonymous_variant 0.27
ccsA 620029 c.139C>T synonymous_variant 1.0
rpoC 764367 p.Gly333Ala missense_variant 0.25
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777883 p.Gly200Arg missense_variant 0.31
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406101 p.Pro414Ser missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1473067 n.1222C>T non_coding_transcript_exon_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.36
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.26
PPE35 2170568 p.Ile15Met missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519071 p.Asp319Glu missense_variant 0.26
fbiD 3339734 p.Ala206Gly missense_variant 0.83
fbiD 3339746 p.Ala210Gly missense_variant 0.27
fbiD 3339751 p.Ala212Pro missense_variant 0.33
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568427 p.Arg85Cys missense_variant 0.18
whiB7 3568431 c.249C>G synonymous_variant 0.29
rpoA 3878575 c.-68C>T upstream_gene_variant 1.0
rpoA 3878608 c.-101C>G upstream_gene_variant 0.24
rpoA 3878618 c.-111A>C upstream_gene_variant 0.22
rpoA 3878637 c.-130G>C upstream_gene_variant 0.25
rpoA 3878641 c.-134C>G upstream_gene_variant 0.76
clpC1 4038318 p.Pro796Leu missense_variant 1.0
embC 4240409 p.Pro183Ala missense_variant 0.31
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246527 p.Ala5Gly missense_variant 0.33
embB 4247016 p.Ser168Trp missense_variant 0.18
embB 4248328 c.1815G>C synonymous_variant 0.19
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407560 p.Ser215Pro missense_variant 1.0