TB-Profiler result

Run: ERR11050344
Summary

Run ID: ERR11050344

Sample name:

Date: 02-04-2023 23:48:08

Number of reads: 3985850

Percentage reads mapped: 99.59

Strain: lineage4.6.5

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
lineage4.6.5 Euro-American T;LAM None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576106 c.759C>G synonymous_variant 0.21
mshA 576616 c.1269G>C synonymous_variant 0.12
rpoC 764367 p.Gly333Ala missense_variant 0.2
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777883 p.Gly200Arg missense_variant 0.23
mmpL5 777974 c.507C>T synonymous_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.29
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168708 c.1905T>C synonymous_variant 1.0
PPE35 2169149 c.1464G>A synonymous_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.18
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519071 p.Asp319Glu missense_variant 0.17
folC 2746995 p.Val202Ile missense_variant 1.0
pepQ 2860159 p.Ala87Gly missense_variant 0.16
fbiD 3339734 p.Ala206Gly missense_variant 0.58
fbiD 3339751 p.Ala212Pro missense_variant 0.26
Rv3083 3449768 p.Thr422Arg missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568427 p.Arg85Cys missense_variant 0.17
whiB7 3568428 c.252A>G synonymous_variant 0.3
rpoA 3878641 c.-134C>G upstream_gene_variant 0.53
clpC1 4040859 c.-155T>C upstream_gene_variant 1.0
embC 4240409 p.Pro183Ala missense_variant 0.19
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246527 p.Ala5Gly missense_variant 0.41
embB 4247020 c.507C>G synonymous_variant 0.21
embB 4248328 c.1815G>C synonymous_variant 0.21
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
PPE35 2168993 c.1463_1619del frameshift_variant 1.0