TB-Profiler result

Run: ERR11050606
Summary

Run ID: ERR11050606

Sample name:

Date: 03-04-2023 13:00:58

Number of reads: 5411714

Percentage reads mapped: 99.66

Strain: lineage4.7

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7270 c.-32C>T upstream_gene_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.14
mshA 576113 p.Arg256Gly missense_variant 0.26
mshA 576456 p.Val370Gly missense_variant 0.34
mshA 576616 c.1269G>C synonymous_variant 0.33
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777883 p.Gly200Arg missense_variant 0.25
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473503 n.-155G>T upstream_gene_variant 1.0
rrl 1474294 n.637C>G non_coding_transcript_exon_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.22
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.43
PPE35 2170675 c.-63G>C upstream_gene_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519071 p.Asp319Glu missense_variant 0.16
thyA 3074589 c.-118G>T upstream_gene_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.4
fbiD 3339751 p.Ala212Pro missense_variant 0.19
Rv3083 3449856 p.Met451Ile missense_variant 1.0
whiB7 3568426 p.Arg85His missense_variant 0.11
fbiA 3641282 p.Ile247Asn missense_variant 0.99
rpoA 3878641 c.-134C>G upstream_gene_variant 0.65
embC 4240409 p.Pro183Ala missense_variant 0.38
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246527 p.Ala5Gly missense_variant 0.15
embB 4246572 p.Phe20Tyr missense_variant 0.11
embB 4247331 p.Trp273Leu missense_variant 1.0
embB 4248328 c.1815G>C synonymous_variant 0.26
embB 4249732 c.3219C>G synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0