TB-Profiler result

Run: ERR11050860

Summary

Run ID: ERR11050860

Sample name:

Date: 04-04-2023 00:15:17

Number of reads: 2524749

Percentage reads mapped: 99.58

Strain: lineage4.3.2

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.2 Euro-American (LAM) LAM3 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491315 p.Gly178Ala missense_variant 0.19
mshA 576442 p.Cys365Trp missense_variant 0.47
mshA 576446 p.Thr367Pro missense_variant 0.29
mshA 576453 p.Val369Gly missense_variant 0.4
mshA 576616 c.1269G>C synonymous_variant 0.13
rpoC 764367 p.Gly333Ala missense_variant 0.21
rpoC 764995 c.1626C>G synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777883 p.Gly200Arg missense_variant 0.24
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472337 n.492C>T non_coding_transcript_exon_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.34
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.25
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519071 p.Asp319Glu missense_variant 0.33
folC 2746528 c.1071C>G synonymous_variant 0.28
thyX 3067946 c.-1C>G upstream_gene_variant 0.23
thyA 3073868 p.Thr202Ala missense_variant 1.0
thyA 3074657 c.-186C>G upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087816 p.Cys333Gly missense_variant 0.29
fbiD 3339734 p.Ala206Gly missense_variant 1.0
fbiD 3339751 p.Ala212Pro missense_variant 0.38
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878641 c.-134C>G upstream_gene_variant 1.0
clpC1 4038287 c.2418C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246527 p.Ala5Gly missense_variant 0.28
embB 4246529 p.Ser6Gly missense_variant 0.29
embB 4246593 p.Arg27His missense_variant 0.12
embB 4247016 p.Ser168Trp missense_variant 0.23
embB 4247028 p.Leu172Arg missense_variant 0.3
embB 4248328 c.1815G>C synonymous_variant 0.24
aftB 4267981 p.Arg286Gly missense_variant 0.24
whiB6 4338200 p.Asp108His missense_variant 0.25
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0