TB-Profiler result

Run: ERR11067465
Summary

Run ID: ERR11067465

Sample name:

Date: 04-04-2023 20:51:20

Number of reads: 2034558

Percentage reads mapped: 99.67

Strain: lineage4.7

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
ethA 4327229 c.244delC frameshift_variant 1.0 ethionamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.17
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474294 n.637C>G non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519099 p.Ala329Thr missense_variant 1.0
ahpC 2726728 p.Arg179His missense_variant 1.0
alr 3840618 p.Asp268Gly missense_variant 1.0
clpC1 4038554 c.2151C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246584 p.Arg24Pro missense_variant 0.27
embB 4247024 p.Pro171Ala missense_variant 0.23
embB 4249732 c.3219C>G synonymous_variant 1.0
ubiA 4269933 c.-100C>G upstream_gene_variant 0.99
whiB6 4338230 p.Leu98Val missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0